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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af8c09ebc4d77f90563d0add81813f512ecbc20c06b1661e56f7783d4d4e33e6' 
  AND token = 'a+5KWYoXoMpap3R9h0eUvYQZtdb4fIHsjbqGVLupWuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}