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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c21b87d1942f4c0085ffb2d3e65e82aa77bd4df8145351be0f48bf4bc3068d44' 
  AND token = 'YuWPOp906hoiudmqvZ5N5gxj6Rt4+69KWkDDaDmEmfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}