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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26ecf45363902b199a98bea3cdce3c43851ff81733034d84faf18575ac6f2c5c' 
  AND token = 'cH+3yd8+i26T/qdkXrMPHiY7u4ryMnqt2JWxBFCO3zE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}