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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a54d90942b73181ca906148cf9f1bceb3e1565be61b1ed51159b209f4a8e5c' 
  AND token = 'OY46AQUH7a/znIlAZgNap4c1WO6BEMtL70av4mv2FTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}