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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b747014f12d3231a51776c7c0b388c1c1247307f9f03b59bb5a74e84f33233d5' 
  AND token = '2Tc2bJFuAF0BT3pk3GzNyD/TIOVqLhvl+2Of5W5AT8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}