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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b97f3892137a6572e5b50c5e8849d8af2c64bda20895f98b081506b950e977c' 
  AND token = 'JpWJJmn1xL7y0vM7uWq2/t+5UArnrrJxuUOROfppSYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}