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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ecda5274a1d148c4eefb7f1c8adf63b1df3e28095d0ce885f02e613b7304983' 
  AND token = 'YlEMSdOANW9nKUQEBUHgk5vC8vbhXUXT859j1ADT3Z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}