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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '653954a7430d6fc854cd087bbe90c1648da75667932a33a04c75f95aa0cfd300' 
  AND token = 'z363TcAO1CXZ4ahnFEb1o6mUbJUDYBWLHgS9XiRMv70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}