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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a495c5ad0783aee046118c7e9d6d2f37114083e639e906430db14eb604a925d' 
  AND token = 'p0IFXkQUMVworoq4yEvPO5t4lNW4nQ5so4cmKaEZrYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}