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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe3fbb793c19e6f2902b94f4e3d66f765c325e7cd731069daa4bc22639798f53' 
  AND token = 'Xup5dl7WsZ7UJwNU2mMgJiC729IdTxIW2wauXQ9ohjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}