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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4ab43d14dc2bb99eb1f89ac7acf2fe768c74d30d667fbe089f452df3efa243b' 
  AND token = '1Y0gIikNFRzWxxW4lSWnv2UNCgPMdlyFb4DHpPmUBeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}