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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '679dfadda109a2f65c1ef33bcdf941581c9c5cd25b7615759f5f72992e859473' 
  AND token = 'FIJsz2ejQMiQ/dL93GDpwtU3zEeXBRTxfCBk0RL0iJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}