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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb4dfa2f8d4ea45a1e5b30d3f03bde535c79818d592256b2acf5a5fe0fe648b5' 
  AND token = 'Uzj5cB7o329+uaEC+2yxhsdr6KBCVECJsX++rtttbUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}