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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d48d0cb4b76936cb5304affae4e36815a647f7d1c1bcea0cdce194eefd2196c' 
  AND token = 'XB6q9OuHPozLnI9/WJfw8ACL3Tslfjti5Gh1dhSX3Xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}