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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0022802814e7a158c9a70f4955b7b24575a01014ba4224783a19bdfb07c1836b' 
  AND token = 'NLRPMZJbb68lDm5xcDRA/GU+W1UDFSP/uZHk7QGwJcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}