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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4caa0cb5248f4cd58a31e423919304267dc3ef3653619be93415168a2b02e866' 
  AND token = 'FLNUB3WB9ZffibPs8PBiBDZOaISkIZEBNZBZEYta+Jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}