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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8112c99a4eb7551cccb3fbc536586fb4da0ec1d1c31f090c2c26551013b8903b' 
  AND token = 'fib7kJcTES63nRdEkaxmp9cMSeIBgdeXCDSFqtzCkys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}