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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c246b97a84f0fafb41137a072dcae2d0dcc9eacf6deac63a70537864cc66da8' 
  AND token = '9Nid9SPL+JZhq4t7xd2G4z9n1oBa4yBnGUsCjDTrx0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}