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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '854db2441e30293c7e3a79d68dcf546fc795f5b3d4b9770840a6ae1c3de9ce10' 
  AND token = 'F/STX8m+SmqurrsSJJm1VngD6UdZDmvDn1cTPj2e/Pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}