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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '756a85d9862af89c4c7b77b5adf1142d260d042ed2229151d48dabd090650833' 
  AND token = 'UDFyGWp04Ks5Hqc1M8LNF/3XVf22Phx2Z8tKTCaT6QA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}