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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91ce2ecfa9d1db3f8b7c5c5aa0da0c8113f57be27bf361039b75284a37374565' 
  AND token = 'vixKdw22c+dPyyXSroRWHpHtax4cXCgA4N5OH1ZuLiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}