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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b6bf43041bff4dc106d1f13f40cf7fc40b8eb1b635b10b1c43ce36f01348bba' 
  AND token = 'jKTGwKrIUUVHTl6mkOfV3Fvh8G8Ycw210zSo0yTkJ9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}