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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '879cd002908716cac1b5dea0302aeb28fa6e1a08d5df8f6cdc9bf48741489f57' 
  AND token = 'rlckaF0KVRMtdoZFxPXyjX+kI2jxNwFE+RwDXpvtrQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}