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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33fa70a7181c6e1f091aaae8c01c71de7c31a51575939659ee9b5b7ce2812f01' 
  AND token = 'uZ4Wg3fLctbWvo191TkuvCxH0hFHB9+mb3YG0p0xGjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}