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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61b9732f028b66be519a71bdda4b2b7ff64632d8dd54131879e250bca8d27f0d' 
  AND token = '0+8T3I4kmpzW8++tII01V9x+SuVXPcEEZ+oAumdLHWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}