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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6db871365189e867a46a45820a99a299526f7193122ea0e3d05da28f56d771ac' 
  AND token = 'gHFaP6OGZYGZnC+sNAUO01V7IOv6EaOXpOanQpvJlyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}