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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14593dc389750805ef517398214371965980c91f35822713b04775cf2115903d' 
  AND token = 'Wv3xxnDsRiSfofX0oDjSuFHsOgH44NNaxgIWopgRZrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}