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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ccde421f06cf5bee8b8b7adb8cad31fcdb0c0bac0fbcf846c2aaa4356eaf83' 
  AND token = 'ufWBx1i4O13ypXqdh++sT8u1OVi+RlgKSc2Hi2rrgzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}