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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fb6935bb017f994d5cb831e5935a11fea747efeede7e7e03006f1d8e21b4fc3' 
  AND token = 'iZ//kfLzKh60JpkUbOuo4BmsRm4ABDhW1BYR2JDAUSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}