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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8388bfe39ac5c502f1c14af60f764aba9ba393ee3f9e9ca1e1e531d4796bc0bb' 
  AND token = 'GE7hgOswr2eIbFMjVaQGFir6i2+6WgXq3OZFiWsK2GE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}