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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f3e3446cc9d1a08f8b79a68ad566d83e7a900cfb5f83dc783dc3e2d4db0040a' 
  AND token = '24BDVxW7KIpg3/MdqD4eaf2auUTN0YQFdAh6RKCX0HM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}