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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b3c3aa237107d9108175cc168be1186a0d62d519fa1a34f7c2be9a6717d1b20' 
  AND token = 'QnFyEHUy9s0Y6nhxMXLFsIXfcAtqVlUYApFyFepLuc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}