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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b52d97f1cfdbf150eba48e7c37dbaf0f2cd5b8e359a832a098276623a4e95960' 
  AND token = 'xP5hks3LRfiYnzY14+XY9/7IXmEnxky9uDwbK3F0qKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}