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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '338c83dc514d8d4843659199912199fab39a32a22597c7025f54e64ddeddd2a1' 
  AND token = '1EsmVOMsB5r2GLdeRhmWPJS16ZimSW8qp5OPg3i6l3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}