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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e75a92958795c180542abb72f780943d64f5eb59d858574d23271ed60ff307f' 
  AND token = 'Y6M366u9Br0pC0A3LEiTqCobgWygHZH/C26Bv1Jlrkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}