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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f42f5794621c42d2926716d6ad9491423be0d3749b05501707a01afae6e42d2' 
  AND token = 'oyuG8dE8KMeXyvWevQKaISpxHyALE/Vw5bxaXUlMx2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}