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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cfd391d2ebcbbf46e1a63412f7b4205b442e8b64f0422631c858c49b3379f08' 
  AND token = 'sxQR6exy8RTPGOt5CjXJkc4MiVfkhYvNYUJJkrDoF3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}