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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eee91b0b0cb17ac5c667bdd46a43344d27b752dd4173da3d2bdb15c3e37f9b2' 
  AND token = 'Am1aARpLXIw7OgW23e0btuu6z0XswpGQz6SoZH2Pjs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}