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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e007a52aa9f87b07f1e51f8e3a8867bc9767b160ca16ace43a3970f970fb493a' 
  AND token = 'MGtL4vczUC/OdTERO69eXkxUfN1dMKPNYdyDg5QVPS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}