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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '460a6e1b1724a1809ad60bb67bb18c5bdab3fcd6471d61a7f8c17e6d523e60bd' 
  AND token = 'MXiGDIssJQE0d3aMgKiSeirFzvfzNYNhMbAcRGuqweg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}