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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c822b833fca37092c451f7abfaaf0b7c38203a81cec2e97d9be706da082d856' 
  AND token = '3IwM4MliWl+wIXpu3F+M8PzDwyzoMw6SK9jX5NAiApE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}