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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25368fd2c39e756df1f29874deb6afc6741e30103dbe16f278492a74cc665a33' 
  AND token = 'LOiyjU5xdAHUgsJ5W498gf5dOwmr7jyVanAVCoEVTh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}