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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95e396e5d47b88b7904bbd4392a59a5c2427eb8a815d4175bfeff253e04d3353' 
  AND token = 'y2t8s27m3Hj+OFXwRoX4f0V7vdBi8w6His2PcB27FS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}