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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f4c64cdf88b235ae9ff33bc3a9a7d1f245105405b6c2f9b8666e8854981ca82' 
  AND token = 'kwh5rHW96lcwltb6rqssrrpSBqTzZ6dclJ3ntiiA5K8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}