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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b948491ad58c2f645acae059b77b3caeb375008df9eb361462d2ed00bf2ed09' 
  AND token = 'H3z54K0Xx60fH15w+9MfyldM0Zl8w2YXdbDM9mQZNOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}