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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a27b333625eb59193daba3b8738b6ee55bc4de15b30013cd358387022343acd' 
  AND token = 'TA0/cp82TCDUBPPzC5ssE7mZ3jfKhPfxf0Z25G4IcC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}