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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c5c370df970c32fe9d0868d740fed01fe535d5a28c08da5dde7d0d9f1d8b39e' 
  AND token = '0hISsA2lmMqAmOhC7xMdzTfTqLfcQt0q4M/mmE38qQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}