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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a1b730bce9d833f432e1aa0e7f0f7f1e32151d16747a79ca07d01b669eca908' 
  AND token = '9cLDCJdmNRHt8tmjM5C9jKJOPUKt7m7aTezNNZUPNR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}