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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74bbef1c0aee2110e2bb8e7476e1487cbfdfc253849ac650acc78969cb064598' 
  AND token = 'Rq59mEp8c7TeBZ2ucDNJgT9n+x5U5Eo8X9xFh+qYtzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}