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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97f4c136d1018b902564d842eb84c8fffe4b34536cd048a94e65ad28dda2418b' 
  AND token = 'k0MH1JGTCoEQRqM3k6hrr3hpH/PghArWUFQ3PgGfvTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}